Differential schwann cell migration in adult and old mice: an in vitro study.

Mesenchymal Stem Cells as an Alternative for Schwann Cells in Rat Spinal Cord Injury

Background: Spinal cord has a limited capacity to repair therefore, medical interventions are necessary for treatment of injuries. Transplantation of Schwann cells has shown a great promising result for spinal cord injury (SCI). However, harvesting Schwann cell has been limited due to donor morbidity and limited expansion capacity. Furthermore, accessible sources such as bone marrow stem cells ...

P27: KCNK2 and Adhesion Molecules in an in-Vitro Blood Brain Barrier Model

Two-pore domain potassium channels, like KCNK2, are known to play an important role in inflammatory diseases such as multiple sclerosis (MS). Upregulation of cellular adhesion molecules in mouse brain microvascular endothelial cells (MBMECs) of Kcnk2-/- mice resulted in elevated leukocyte trafficking into the central nervous system under inflammatory conditions. The current project aims to gain...

Comparison of Neonatal and Adult Mice-derived Sertoli Cells in Support of Expansion of Mouse Spermatogonial Stem Cells In vitro

Efficacy of optimized in vitro predegeneration period on the cell count and purity of canine Schwann cell cultures

Objective(s): Predegeneration is a standard technique to obtain mitotically activated and enriched cultures of Schwann cells (SCs). This study, for the first time, evaluated the impact of various duration of predegeneration on cell yield and enrichment of SCs from dog peripheral nerve. Materials and Methods: Dog sural nerves were subjected to 5, 10, 15 day-long in vitro predegeneration. The tot...

P-123: Impact of Oxidative Stress on Differentiation of Testis in Mice

Background: Antioxidants and reactive oxygen species (ROS) are in balance in the body. Whenever the balance between these molecules is disrupted towards an overabundance of ROS, oxidative stress (OS) occurs. There are evidence that glutathione as an intracellular antioxidant plays an important role against ROS in female reproductive system. Regarding the effect of BSO as a selective inhibitor o...